Being an actor is about the capacity to adapt to any random role, be in positive or negative. Some names stand up in the crowd with their outstanding performances, as well as the diversity of their roles. Johnny Depp is probably representative from this point of view.
He has been pretty much everyone and everything. Jared Leto’s capabilities to lose and drop weight overnight are not to be overlooked either. When it comes to actresses, Natalie Portman is certainly the first one that goes through your mind. She does know what it takes to adapt and make the difference in any role.